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Joined 1 year ago
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Cake day: June 12th, 2023

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  • DRx@lemmy.worldtoADHD memes@lemmy.dbzer0.comGetting up to speed
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    5 months ago

    Well, as a pharmacist whose been stable on 50mg of vyvanse for more than 3 years, your wife and Doc are both incorrect…

    Both are stimulants, yes, but

    Vyvanse is an amphetamine and works to produce more neurotransmitters you don’t already have.

    Cocaine is a reuptake inhibitor… thus preventing the breakdown of neurotransmitters you do already have.

    While fundamentally they may look like they’re doing the same thing, they are in fact 2 totally different mechanisms. Furthermore, in neurotransmitter depletion the effects of cocaine will severely diminish, where as amphetamines will thrive.


  • lol had this happen to me the other day.

    Typically I play classic rock at work like the stones, Beatles, eagles, etc and no one bats an eye and sings along. I played a song off hybrid theory and my tech walked by and went “wow that’s a throw back!” I immediately had a mini midlife crisis. That album is almost 24 years old btw, and I still remember the day I bought it.


  • I believe Jesus also said

    Matthew 7:5 Hypocrite! First remove the plank from your own eye, and then you will see clearly to remove the speck from your brother’s eye.

    So maybe we should focus on our own paths in life rather than someone else’s life decision that has 0 bearing on whether you or I go to heaven or hell?

    I mean why people are so obsessed with what people do in their own home, on their own dime, and their own time is beyond me.

    Christofacists just want to control others. They don’t care what Jesus said. They don’t want to FOLLOW Jesus, They want to BE Jesus and tell others how to live.



  • So unless you live in an area with fiber, asymmetrical speeds are pretty typical… I’m not sure if it is because it’s all coax so there are infrastructure limitations? But it’s actually gotten faster because 6 months ago my upload was only 30 mbit/s.

    Once fiber is in my area I’ll switch to that, but symmetrical will add more cost…but of course it will lol



  • According to the CDC:

    more than 93.1% of abortions were performed at ≤13 weeks’ gestation; a smaller number of abortions (5.8%) were performed at 14–20 weeks’ gestation, and even fewer (0.9%) were performed at ≥21 weeks’ gestation.

    1. So, 93.1% aren’t even fetuses yet, they are zygotes (which is a clump of cells)

    2. the other 6.9% are fetuses not babies.

    • A baby is a non-clinical term for an “infant” (def: a very young child under the age of 1 years old) that has bodily autonomy separate from the mother.

    So, to recap, abortion is not killing a baby



  • No, not aspirin. We know aspirin very well in the medical community.

    TBF there are drugs out there that we do not know the MOA of, like methocarbamol (from the national institute of health: “The exact mechanism of action of methocarbamol remains unknown; similarly unknown is the relationship between musculoskeletal pain and muscle spasm” lol)

    So for long term safety, it is based on animal and human studies. These studies happen for multiple years prior to being put on the market (for the most part, though that is a story for a different day). Then after the drug is on the market, the drug company is required to do “Postmarket Clinical Studies” to show that their drug is still doing what it was initial shown to do; furthermore, to look for safety events of said drug.

    A really famous case of a bungled postmark study was Vioxx. Vioxx is/was a Cox-2 specific pain medication. In the initial and postmarket studies they found that it had an increased risk of heart attack (in some cases up to 88% increased risk). The company Merck held the information from the public and FDA. They were forced to take the drug off the market in 2004. Technically in short bursts Vioxx was probably safe, but long term it was not.


  • Well how specific is enough to say we do or don’t know how a drug works?

    In particular we do know that ASA and other NSAIDS work by inhibiting the activity of the enzyme called cyclooxygenase which leads to the formation of prostaglandins that cause inflammation, swelling, pain and fever. It blocks both COX 1 and 2, though only COX 2 is responsible inflammation. Furthermore, The antithrombotic action of aspirin is due to inhibition of platelet function by acetylation of the platelet cyclooxygenase at the functionally important amino acid serine529.

    Now contrast ASA with Acetaminophen …

    We know that Acetaminophen also inhibits COX, but only in the CNS and not peripherally. Also, it is only thought that it potentially blocks pain signals via the serotonergic pain pathway.

    I would say we know a hell of a lot about aspirin … Acetaminophen not so much on the MOA side of things, however it has been studied so much that we know the safety/toxicity profile like the back of our hands. Either way probably not the best 2 examples to use for your argument.



  • Christian brings up some great points worthy of consideration; however, if your going to use traditional routing through their network (A/cname) your still doing the same thing. CF will still see your traffic.

    The second thing I should say is, I only use zero trust for websites I share with family. So, I have a Searxng and wef/voyager dockers running through zero trust.

    For admin, homeassistant/iot/ip cams, I use an always on IPSec vpn on my iPhone, iPad, and steam deck (take it to work and plug into 3rd monitor) … this is cool because I get 24/7 ad blocking no matter where I am because it routes all my traffic through my pihole at home. This is a great solution for a single person, but I do not want to manage vpn access for multiple ppl. So, I agree with christian in NOT putting admin stuff/sensitive info behind CF at all (zero trust OR tradition web routing) unless you fully trust them. Otherwise do a 24/7 vpn like I do.



    1. Parents are southern baptist and tithe 10% yearly

    2. Constantly complain about socialism, and taxes

    3. Go on mission trips to Haiti to help build homes

    4. Constantly complain about refugees and immigration

    5. Claims to have lgbt, black, etc minority friends

    6. Sees nothing wrong with current Supreme Court trend taking rights away from said minority groups…

    7/8. Think of any two things that are opposites between real life, what religion should be about, and politics… and it is someway twisted in a way you wouldn’t think would be possible.

    TLDR: there is no way of dealing with this cognitive dissonance. It is maddening. I’ve gotten to the point of trolling my fam with republican Jesus lol. It’s the only thing that makes me at least laugh about the insanity.




  • Currently my UPS is reporting 207 watts, that’s with a unraid server (3600 + 32GB ram + 2060 super for plex, and 6 drives), a mini pc for pf sense, a rpi 4 running pihole and vpn server, a single poe ap, a modem, and security cameras… it can spike to 250w with multiple encodes going on from family … but overall not bad… I did have a dedicated 20A switch installed for just my network closet as well


  • Thankfully with the knowledge from my server, the switch will be more kind than if I’d never touched Linux before.

    For real man, close to a decade ago I started off with a raspberry pi b+ and literally copying and pasting every code I found, and today I feel I can do almost anything I want in Linux. Moving from tinkering with Xbmc and retropies, to setting up openhan and pi-holes, then moving on to dockers, home assistant, and web-servers to building out a server/networking closet and running cat6 through the house lol

    I love that the steam deck has a desktop mode as well. If steamos was out for desktop AND it supported nvidia (which it currently doesn’t), then that would be my new OS and I’d drop windows today.


  • I have and for the most part it’s actually really good and responsive… live video feeds aren’t working like I want (no live video, just an updated scene every 30 seconds), but house alarm, lights, garage door, outlets, door locks all work great and all of it is through home assistant then to HomeKit … none of my devices are “HomeKit” compatible, I use mostly z-wave and have home assistant parse the info and tunnel though home


  • Yea I completely forgot to mention HomeKit in my comment! Is it kind of generic and do I wish it could do more? Yea, but damn is it nice to tell Siri “goodnight” and all the light in the house go out, the doors lock, and the alarm sets! Plus my partner can use it better than home assistant, and if I need my bro to come watch my house for a week, I can give him access on his phone and revoke it any time!