The problem with using seaweedfs to a back your DBs is more on the filesystem than the implementations of POSIX features. When you are writing to a file, and the connection to seaweedfs breaks (container restart, wifi, you name it), then you might end up with a half-written file. If you upload pictures, this is unlikely, but DBs are doing several writes per second usually. So it is more likely one of those gets interrupted. In my case, my grafana sqlite DB would get corrupted every other week.
What I recommend is using DBs natively in your node’s filesystem, and backing them up to seaweedfs periodically instead. That way your DBs ‘work’ but you can get them running again, and the backup is replicated in the distributed filesystem.
Nomad has host volumes - so you can tell it to mount a folder from the machine on the container, and it will only schedule that container on machines that have that folder. So yes, effectively you pin the workload, thus introducing a SPOF - I do not love it but Grafana only supports sqlite and postgres, so making those HA would require failover setups which is a bit much for a homelab :')
For backing up, you can use the sqlite command periodically (do cron job or Nomad periodic job) and then upload the backup to some external, safe storage (could be seaweedfs or S3!). For postgres you can use something like this.