To me, the first should be ants, they’re practically everywhere and there’s a lot of them
The ants will not listen. The ants will show no mercy.
Ants can make us their slaves if we do not cooperate. They have the largest colonies and are the most organized. However, they have clans and problems just like humans now.
In the UK we call them daddy long legs, I don’t know what they would be called in the US - though I think it might be horseflies(?). Anyway I was told at School that IF they could break human skin, they would be deadly to us - but they haven’t evolved that ability - yet. So I think they would be who I would befriend first - just in case.
Edit: crane flies
The idea that daddy longlegs are highly venomous and just unable to pierce human skin is an urban myth and has no basis in reality. https://www.snopes.com/fact-check/daddy-longlegs/
Mosquitoes. If they were organised and had a goal, they could destroy humans. Imagine if they all line up to suck from someone with loads of diseases to get some viral load and then go and seek out people in positions of power to infect.